General Information
The Curing the Epilepsies 2026: New Horizons Conference will
be held on June 8-10, 2026 at the Natcher Conference Center, building 45, NIH
Campus.
This two-and-a-half-day conference aims to bring together
all stakeholders within the epilepsy research community and will serve as a
critical forum to assess recent advances in basic, translational, and clinical
science; identify persistent and emerging gaps in knowledge; and explore
high-impact opportunities to accelerate progress across the epilepsy spectrum.
As with earlier Curing the Epilepsies conferences, the Epilepsy Benchmark Stewards Committee, coordinated by the American Epilepsy Society, will revise the Epilepsy Research Benchmarks, reflecting recent advances and stakeholder input. These reevaluated Benchmarks are intended to anchor research over the next 5-7 years in the issues that are key to understanding the epilepsies and improving meaningful outcomes for people with epilepsy through research. Participants will be encouraged to articulate transformative
research priorities aimed at four overarching goals:
- Achieving cures for all forms
of epilepsy with no disabling side effects
- Mitigating or eliminating the
often-overlooked comorbidities that compromise quality of life
- Developing strategies to
prevent epilepsy in individuals at risk due to genetic, structural, or acquired
factors.
- Fostering collaboration among
scientists, clinicians, people living with epilepsy, and advocacy communities
CALL FOR ABSTRACTS - NOW OPEN
Priority for selection will be given to early career scientists. Selected presenters will receive an honorarium.
Up to 48 Abstracts will be selected for Poster presentations and Flash-Talks at the conference.
Abstract Submission Deadline extended to April 13, 2026
Meeting Contacts
- Leenders, Adriana +1 301 496 1917 leenderm@mail.nih.gov
Sponsored By
- American Epilepsy Society (AES)
- National Institute of Neurological Disorders and Stroke (NINDS)
Sessions/Agenda
Monday, June 8, 2026-Wednesday, June 10, 2026
08:00 AM-05:00 PM(EST)
Natcher Conference Center
45 Center Drive,
Bethesda, MD - 20892
Curing the Epilepsies 2026: New Horizons
June 8-10, 2026
Day 1:
9:00 - 9:45 AM Session I: Introductions, Setting the Stage for Transformative Epilepsy Research Priorities
Moderator: Vicky Whittemore, PhD; National Institute of Neurological Disorders and Stroke (NINDS), NIH
9:00 - 9:10 AM Welcome
Amy Adams, PhD; Acting Director, National Institute of Neurological Disorders
and Stroke (NINDS), NIH
Jack Parent, MD; President, American Epilepsy Society (AES)
9:10 - 9:15 AM Personal Perspective
Laura Lubbers, PhD; Chief Scientific Officer, CURE Epilepsy
9:15 - 9:30 AM History of the Epilepsy Research Benchmarks
Lori L. Isom, PhD; University of Michigan Medical School
9:30 - 9:45 AM Introduction to the Transformative Epilepsy Research Priorities
Eric Marsh, MD, PhD; Children¿s Hospital of Philadelphia Research Institute
9:45 AM - 12:00 PM Session II: Understanding the Mechanisms of the Epilepsies
Moderator: Annapurna Poduri, MD, MPH, FAES; Boston Children¿s Hospital/Harvard
9:45 - 9:50 AM Personal Perspective
TBD
9:50 - 10:05 AM Epilepsy Genetics Research in 2026 and Beyond
Gemma Carvill, PhD; Northwestern University
10:05 - 10:20 AM Neonatal Screening
Alissa D'Gama, MD, PhD; Boston Children¿s Hospital
10:20 - 10:35 AM Break
10:35 - 10:50 AM Post-traumatic Epilepsy
Aristea Galanopoulou, MD, PhD; Albert Einstein College of Medicine
10:50 - 11:05 AM Late Onset Unexplained Epilepsy
Alice Lam, MD, PhD; Massachusetts General Hospital
11:05 - 11:20 AM FLASH TALKS- 3 talks 5 min each (selected from submitted abstracts)
11:20 - 11:40 AM DISCUSSION
11:40 AM - 12:45 PM Lunch
12:45 - 1:30 PM Poster Session
1:30 - 3:15 PM Session III: Disease Modeling of the Epilepsies
Moderator: Karen Wilcox, PhD; University of Utah
1:30 - 1:35 PM Personal Perspective
TBD
1:35 - 1:50 PM Role of Animal Models of the Epilepsies: What are we modeling and why?
Christopher McGraw, MD, PhD; Northwestern University
1:50 - 2:05 PM Disparities in Genomic Data and Human Model Development
Heather Mefford, MD, PhD; St. Jude Children's Research Hospital
2:05 - 2:20 PM New Approach Methodologies (NAMs) for Research on the Epilepsies
Jenny Hsieh, PhD; University of Texas, San Antonio
2:20 - 2:35 PM Modeling Epilepsy Mortality
David Auerbach, PhD; SUNY Upstate Medical University
2:35 - 2:50 PM FLASH TALKS- 3 x 5 minutes (Selected from submitted poster abstracts)
2:50 - 3:20 PM DISCUSSION
3:20 - 3:35 PM Break
3:35 - 4:35 PM Breakout Groups
4:35 - 5:00 PM Day 1 Wrap Up
Day 2:
8:30 - 10:20 AM Session IV- Translation and Implementation of Treatments for the Epilepsies
Moderator: Alice Lam, MD, PhD, Massachusetts Geneal Hospital/Harvard
8:30 - 8:35 AM Personal Perspective
Leah Schust Myers, Executive Director and Founder FamilieSCN2A Foundation
8:35 - 8:50 AM Rigor and Reproducibility of Preclinical Data
Devon Crawford, PhD; Program Director Office of Research Quality, NINDS
8:50 - 9:05 AM Clinical Trial Readiness - Measures and Biomarkers
TBD
9:05 - 9:20 AM Challenges in Access to Clinical Trials
Dave Clark, MD; University of Texas at Austin
9:20 - 9:35 AM Global Health Research on the Epilepsies: Lessons Learned to Apply to Rural
Healthcare Issues in USA
Edwin Trevathan, MD, MPH; Vanderbilt
9:35 - 9:50 AM FLASH TALKS- 3 x 5 minutes
9:50 - 10:20 AM DISCUSSION
10:20 - 10:35 AM Break
10:35 AM - 1:00 PM Session V: Treatments for the Epilepsies
Moderator: Gemma Carvill, PhD; Northwestern University
10:35 - 10:40 AM Personal Perspective
TBD
10:40 - 10:55 AM Disease Modifying Therapies
Julie Ziobro, MD, PhD; University of Michigan
10:55 - 11:10 AM Emerging Small Molecule Therapeutics
Karen Wilcox, PhD; University of Utah
11:10 - 11:25 AM Drug Repurposing
Alexander Bassuk, MD, PhD; University of Iowa
11:25 - 11:40 AM Devices and Neuromodulation
Gregory Worrell, MD, PhD; Mayo Clinic
11:40 - 11:55 AM Surgical Approaches and Multi-modal Evaluation
Kathryn Davis, MD; University of Pennsylvania
11:55 AM - 12:10 PM FLASH TALKS- 3 x 5 minutes
12:10 - 12: 40 PM DISCUSSION
12:40 - 1:30 PM Lunch Break
1:30- 2:30 PM Poster Session
2:30 - 3:45 PM Session VI: Data Integration to Accelerate Research
Moderator: Brian Litt, MD, PhD; University of Pennsylvania
2:30 - 2:35 PM Personal Perspective
TBD
2:35 - 2:50 PM Data Integration
Joost Wagenaar, PhD; University of Pennsylvania
2:50 - 3:05 PM Big Data in Epilepsy Research
Brandon Westover, MD, PhD; Stanford University
3:05 - 3:20 PM The Use of AI in Epilepsy and Neurological Disease
Samden Lhatoo, MD; University of Texas, Houston
3:20 - 3:35 PM FLASH TALKS- 3 x 5 minutes
3:35- 3:55 PM DISCUSSION
3:55 - 4:10 PM Break
4:10 - 5:00 PM Breakout Groups
Day 3:
8:30 - 10:00 AM Session VII: Defining the critical priorities for epilepsy research?
Moderator: Annapurna Poduri, MD, MPH, FAES; Boston Children¿s Hospital/Harvard
Panel:
= Jenny Hsieh, PhD; UTSA
= Alice Lam, MD, PhD; Massachusetts General Hospital
= Joost Wagenaar, PhD; University of Pennsylvania
= Karen Wilcox, PhD; University of Utah
= Greg Worrell, MD, PHD; Mayo Clinic
10:00 - 11:00 AM National Plan - what are the next steps?
Moderator: Daniel Lowenstein, MD: University of California San FranciscoPanel:
= Katie Collins; G2G Consulting/EAN/AES
= John Ingram, MD, University of Mississippi
= Jaideep Kapur, MBBS, PhD; University of Virginia
= Walter Koroshetz, MD
= Katy Lalor, MD; University of Alabama at Birmingham
= Laura Weidner; EFA
11:00 - 12:00 PM Wrap up -- What Comes Next?
Moderators: Lori Isom, PhD and Eric Marsh, MD, PhD
12:00 PM Conference Adjourns
Logistics
Visitor Information
The conference will be held in the Natcher conference
center, building 45 on the NIH Campus, Bethesda, MD.
For planning a visit to the main NIH campus: You can find
maps and other helpful travel-related information on the NIH Visitor
Information page.
Security
All NIH visitors must go through a security clearance at the NIH Gateway Center to receive a visitor's badge. Visitors may be required to pass through a metal detector and have bags/purses inspected or x-rayed. All visitors must present a government-issued photo ID to enter the campus. Please allow 1 hour to get through the security clearance.
IMPORTANT INFORMATION: VisitNIH is focused on implementing updated security requirements for non-U.S. person visitors, while respecting the NIH mission and improving the overall visit experience for all visitors.
Directions
The Natcher
Conference Center (Building 45) is located on the NIH main campus. Natcher
Conference Center is a 5-minute walk from the NIH Gateway Center visitor
entrance or a campus shuttle is available (stop at Building 45).
Paid visitor
parking is extremely limited at the National Institutes of Health. Please
consider other options, such as public transportation, taxi and uber/lyft. If
arriving by rideshare or taxi, ask to be dropped off at the Medical Center
Metro stop.
Public
Transportation
The Washington D.C. Metrorail system has a station on the NIH campus called Medical Center. Upon exiting the station, it is a short walk to the NIH Gateway Center. Metrorail service is available from Ronald Reagan Washington National Airport and from Union Station (access to Amtrak and other commuter trains). Take Metro's Red Line to the Medical Center station.
Parking
If you must drive, take the Wisconsin Avenue exit from the Capital Beltway (Interstate Route 495) and go about 1.5 miles (2.4 kilometers) south on Wisconsin Avenue toward Bethesda, staying in the right lane. Do not turn onto South Drive, instead go another approximately three-tenths of a mile (500 meters) and turn right onto "NIH Gateway Drive". This one-way road leads directly to the Gateway Center Vehicle Inspection Station. Limited parking is available for a fee. Vehicles should enter via NIH Gateway Drive off Route 355-Rockville Pike (southbound only) and park in the MLP 11 garage (see map). Cost: $2 per hour for the first three hours, $12 daily maximum. For more details see Gateway
Center Map
Epilepsy Research
Benchmarks
The Curing the Epilepsies conference is held every 5-7 years to
critically examine the progress in epilepsy research and to help set an agenda
for years to come. An important and fruitful outcome of the discussions from
the previous conferences (2000, 2007, 2013 and 2021) has been the production of
the Benchmarks for Epilepsy Research, which reflect current priorities
shared across the epilepsy community for clinically meaningful research advances
in understanding and treating epilepsies. Since their introduction in 2000, the
Benchmarks have served as guideposts in the epilepsy research community by
bringing attention to goals such as preventing epileptogenesis, addressing
features of epilepsy beyond that of seizures, and confronting the challenge of
sudden unexpected death in epilepsy (SUDEP).
Conference
Breakout Sessions
In 2025, the AES Epilepsy Benchmark Stewards Committee started the
process for revising the 2021 benchmarks. Recent progress has been assessed across
the 2021 benchmarks to inform a set of new research priorities. And with
revisions to be made based on public comments received through a crowdsourcing
campaign to be conducted this spring before the conference. More information on the ideascale campaign to
come soon!
On the first two conference days we have planned in-depth
discussion breakout sessions inviting all meeting attendees to provide further input
for updates to the Epilepsy Research Benchmarks. Breakout groups will meet to
discuss potential updates to the content and organization of these goals to set
new research priorities. On the third and final conference day, a full group
session will develop a formal summary of the proposed new research priorities. It
is our aim that discussions are guided by the presentations and general
discussions had during the conference sessions.
2021
AES/NINDS Benchmarks for Epilepsy Research
Area I: Understand the causes of
the epilepsies and their relationship to epilepsy-associated neurologic,
psychiatric, and somatic conditions.
Area II: Prevent epilepsy and its
progression.
Area III: Improve treatment options
for controlling seizures and epilepsy-related conditions while limiting side
effects.
Area IV: Limit, treat, or prevent
co-occurring conditions associated with epilepsy across the lifespan in general
and special epilepsy populations.
Click here
for an overview of the 2021 Benchmarks and the AES Benchmarks Stewards
Committee
CALL FOR ABSTRACTS
Abstract Submission Deadline is April 13, 2026.
Investigators are invited to submit abstracts for selection for a flash-talk or poster presentation at the conference. Investigators, especially early career investigators, are encouraged to submit abstracts addressing novel or innovative research priorities and/or demonstrate progress towards the 2021 epilepsy research benchmarks. The poster session will provide an important venue to discuss big ideas on the Epilepsy Research Benchmarks moving forward.
Posters: Abstracts will be reviewed by a Program Selection Committee for suitability of content focused on an area of epilepsy research addressed in the benchmarks or an identified gap area. Up to 48 abstracts can be selected for poster presentations at a dedicated poster session on the first day of the conference.
Flash talks: In addition, the Program Selection Committee will select up to 15 abstracts for 5min flash-talks, 3 talks at each of the 5 main sessions of the conference.
Conference Sessions:
- Understanding the Mechanisms of the Epilepsies
- Disease Modelling of the Epilepsies
- Treatments for the Epilepsies
- Translation and Implementation of Treatments for the Epilepsies
- Data Integration to Accelerate Research
You can submit your abstract when you register for the conference.
If you want to be considered for the flash talks, indicate this by selecting platform presentation or both under preference
All selected abstract presenters, poster and poster/flash talks, will receive an honorarium
Abstract Submission Instructions
Title
Enter the title of your abstract/poster in Title Case (i.e. capitalize the first letter of each word, except prepositions)
Author Names
Enter the author names in order, formatted as follows:
Author Last Name, First Name Middle Initial (if desired)
The First Author MUST be the presenter
If authors have different affiliations, use a superscripted number (e.g., 1, 2, 3) to indicate each unique affiliation
Author Affiliations
List the affiliations of all authors beginning with the presenter
Include the Department/Division, Institution, City, and State
If superscripted numbers were used after Author Names to denote different affiliations, use them to correlate the name with an affiliation
Abstract
Abstracts are limited to 300 words, not including the title, authors, and affiliations.
Each abstract should contain: the research objective (unless given in the title); methods used; a summary of the results obtained; and the conclusions.
The abstracts may include presentations about basic, translational or applied (clinical) research, patient-oriented research, and health services, epidemiological, or implementation sciences research.
Novel and innovative posters are encouraged, though submissions must be based on sound principles of rigorous research.
All abstracts should address an appropriate topic of scientific discussion. Presentations should not include commercial messages or inappropriate references to specific products, services, or commercial concerns.
Lodging
Please contact hotels directly to make your own reservations. The following hotels are located in the area and near Metro Red Line stations.
The Bethesdan Hotel, Tapestry Collection by Hilton
There is a general attendee courtesy sleeping room block at The Bethesdan Hotel, Tapestry Collection by Hilton, Use this link to book or use group code: 90T when booking on the hotel website.
(near
Bethesda metro station; hotel is 0.8miles from the NIH Gateway Center security
entrance)
8120 Wisconsin Avenue, Bethesda, MD 20814
301-652-2000
https://www.hilton.com/en/hotels/wasbaup-the-bethesdan-hotel
Hyatt
Regency Bethesda
(near Bethesda metro station)
One Bethesda Metro Center, Bethesda, MD 20814
301-657-1234
http://bethesda.hyatt.com
Marriott Bethesda Downtown at Marriott HQ
(near Bethesda metro station)
7707 Woodmont Ave, Bethesda, MD 20814
301- 276-7707
https://www.marriott.com/en-us/hotels/wasbd-marriott-bethesda-downtown-at-marriott-hq/overview/
Hilton Garden Inn Bethesda Downtown
(near Bethesda metro station)
7301 Waverly Street, Bethesda, MD 20814
301-654-8111
https://www.hilton.com/en/hotels/wasbtgi-hilton-garden-inn-bethesda-downtown
Bethesda North Marriott Hotel & Conference Center
(near North Bethesda metro station)
5701 Marinelli Road, Bethesda, MD 20852
301-822-9200
http://www.marriott.com/hotels/travel/wasbn-bethesda-north-marriott-hotel-and-conference-center/
Canopy by Hilton Washington DC Bethesda North
940 Rose Avenue, North Bethesda, MD 20852
301-882-9400
https://www.canopybethesda.com/
PLEASE NOTE: NIH has no affiliation or preference for any hotel listed, and this is not an exhaustive list.
