The Neurosciences: Degenerative Disorders, Neuroplasticity, & Intersection with Glycoscience - In-Person Session
09:00 AM-05:00 PM(EST)
Virtual
Videocast,
Bethesda, MD - 20892
Max.Capacity: 500 No Participants
Agenda:
The Neurosciences: Degenerative Disorders, Neuroplasticity, & Intersection with Glycoscience
September 8 & 9, 2021 (virtual)
Co-Chairs: Dr. Catherine Leimkuhler Grimes, University of Delaware; Dr. Ronald Schnaar, Johns Hopkins School of Medicine; Dr. Austin Yang, NIA; Dr. Kiran Vemuri, NIDA.
Themes to be addressed in this symposium: Neurodegenerative Disorders, Neuroplasticity & Therapeutics, New Tools from the CF-GSP for Research in the Neurosciences
September 8
10 a.m., Welcome & Introductions, Symposium Co-Chairs
Session I.
Chair, Dr. Catherine Leimkuhler Grimes, University of Delaware
10:15 a.m., Dr. Matthew Macauley, University of Alberta
Understanding the Role of Siglec-3 (CD33) Isoforms in Microglia and Alzheimer's Disease Susceptibility
10:45 a.m., Dr. Emilia Vitale, Institute of Biochemistry and Cell Biology, National Research Council of Italy
CD33 3D-Structural Analysis Suggests a Novel Hypothesis in the Risk for Dementia
11:15 a.m., Dr. Rishi Kulkarni, Stanford University
Sialoglycans - A New Axis of Communication between Microglia and Neurons
11:45 a.m., Dr. Ronald Schnaar, Johns Hopkins School of Medicine
A Shared Siglec-3/Siglec-8 Ligand in Human Brain
12:15 p.m., Lunch
Session II.
Chair, Dr. Ronald Schnaar, Johns Hopkins School of Medicine
1:00 p.m., Dr. James Fawcett, University of Cambridge
Perineuronal Nets, Memory and Memory Restoration
1:30 p.m., Dr. Marina Guizzetti, Oregon Health and Science University
Glycosaminoglycans, Astrocytes, and Brain Development
2:00 p.m., Dr. Linda Hsieh-Wilson, California Institute of Technology
Glycosaminoglycans: Chemical Tools and Roles in Neuroplasticity.
2:30 p.m., Dr. Manveen Sethi for Joseph Zaia, Boston University School of Medicine
Roles of Matrisome Molecules in Neurological Diseases
3:00 p.m., Dr. Hannes Buelow, Einstein College of Medicine
Specific Heparan Sulfate Codes in the Nervous System
3:30 p.m., Round table discussion
Moderators: Dr. Austin Yang, NIA, NIH & Dr. Ronald Schnaar, Johns Hopkins School of Medicine
4:30 p.m., Adjourn
The Neurosciences: Degenerative Disorders, Neuroplasticity, & Intersection with Glycoscience
September 9
Session III.
Chair, Dr. Austin Yang, NIA, NIH
10:00 a.m., Dr. Karen Duff, UK Dementia Research Institute
Pathogenic Mechanisms Driving Tauopathy
10:30 a.m., Dr. Bradley Hyman, Harvard University, MGH
Differential Drivers of Alzheimer¿s Disease
11:00 a.m., Dr. Steven Finkbeiner, University of California San Francisco
Dynamics of Protein Misfolding and Stress Resilience Revealed with Robotic Microscopy and Artificial Intelligence
11:30 a.m., Dr. David M. Holtzman, Washington University School of Medicine
The Role of APOE, Astrocytes, and Microglia in Abeta and Tau-mediated Pathogenesis
12:00 lunch
Session IV
Chair, Dr. Kiran Vemuri, NIDA, NIH
1:00 p.m., Dr. Albert Wong, University of Toronto
Mouse Models for Psychiatric Disorders
1:30 p.m., Dr. Robin Polt, University of Arizona
Control of Membrane Affinity via Glycosylation: Brain-Penetrant GPCR Agonists from Endogenous Neurotransmitters and Hormones
2:00 p.m., Dr. Kim D. Janda, The Scripps Research Institute & The Skaggs Institute for Chemical Biology
Examining Xenoreactive Antibodies to Address Cocaine and Fentanyl Abuse
2:30 p.m., Dr. Robert Kennedy, University of Michigan
NextGen Microdialysis for Multiplexed In Vivo Chemical Monitoring with Higher Spatial and Temporal Resolution
3:00 p.m., Dr. Christina Woo, Harvard University
Writing and Erasing O-GlcNAc from Target Proteins in the Brain
3:30 p.m., Round Table Discussion
Moderators: Dr. Kiran Vemuri, NIDA & Dr. Catherine Leimkuhler Grimes, University of Delaware
4:30 p.m., adjourn
(U.S. Department of Health and Human Services)