Day 2, Glyco-Informatics at the Interface of Disease and Data - In-Person Session

Wednesday, April 27, 2022
10:00 AM-03:30 PM(EST)
An NIH Videocast (virtual)
NIGMS,
Bethesda, MD - 20892

Max.Capacity: 1000 No Participants

Agenda:

Session III, Cancer Glycobiology

Chair, Dr. Michael Pierce, Complex Carbohydrate Research Center, University of Georgia

10:00 a.m., Dr. Avery Posey, Perelman School of Medicine, University of Pennsylvania

                        Exploiting Truncated O-glycosylation in Tumors for Immunotherapy 

10:20 a.m., Dr. Melissa Haendal, University of Colorado Anschutz School of Medicine

10:40 a.m., Dr. Stacy Malaker, Yale University

                            A systematic comparison of current bioinformatic tools for glycoproteomics data

11:00 a.m., Dr. Radoslav Goldman, Georgetown University

                             Heparan 6-O-endosulfatases in HNSCC and other cancers

11:20 a.m., Dr. Sriram Neelamegham, State University of New York-Buffalo

                            A Pan-Cancer Analysis of Glycogene Dysregulation

11:40 a.m., Dr. Joshua Klein, Boston University

                             Reducing Ambiguity in Glycoform Assignment Using Retention Time Modeling and Glycan Network Smoothing

12:00 p.m., Panel Discussion 

12:20 p.m., Break

Session IV, Rare Disorders

Chair, Dr. Nancy Dahms, Medical College of Wisconsin

01:00 p.m., Dr. Hugo Bellen, Baylor College of Medicine

                        Glucosylceramides are generated by neuronal activity and transported to glia via exosomes for degradation upon      

                              release of a glial TGFb/BMP signal

01:20 p.m., Dr. Lynn Schriml, University of Maryland School of Medicine

                             Modeling & Integrating Rare Disease Data with the Human Disease Ontology 

01:40 p.m., Dr. Evgenia Shishkova, University of Wisconsin

                             Defining mitochondrial protein function and disease pathology through multi-omic profiling

02:00 p.m.,  Dr. Daniel Graham, Broad Institute

                             Clues from human genetics implicate glycobiology in intestinal barrier integrity and inflammation

02:20 p.m.,  Dr. Chiara Manzini, Rutgers, Robert Woods Johnson Medical School   

                             Developing zebrafish models of dystroglycanopathy

02:40 p.m.,  Dr. Michael Tiemeyer, Complex Carbohydrate Research Center, University of Georgia  

                             GlyGen: A resource for integrating glycoscience knowledge

03:00 p.m., Panel Discussion 

03:00 p.m., Adjourn